T CELL SUBSET AND STIMULATION STRENGTH-DEPENDENT MODULATION OF T CELL ACTIVATION BY KV1.3 BLOCKERS.

Kv1.3 is a voltage-gated potassium channel expressed on T cells that plays an important role in T cell activation.Previous studies have shown that blocking Kv1.3 channels in human T cells during activation results in reduced calcium entry, cytokine production, and proliferation.The aim of the present study was to further explore the effects of Kv1.

This article originated in response to requirement for creation of quantitative evaluation system of passive protection elements resistance, which could be implemented into complex process of technical effectiveness evaluation of property protection systems.It deals with design of model, which could be a basis for estimation Electrolytic of breach